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The real purpose of the scientific method is to make sure nature hasn’t misled you into thinking you know something you actually don’t know.

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Robert M. Pirsig (1928–2017) was an American author and professor. Pirsig was best known for his book Zen and the Art of Motorcycle Maintenance, a contemporary philosophical meditation on how to live.

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Psychedelics and Spirituality with Rick Strassman

Here he describes how he was an active Buddhist meditator for twenty years while he was also engaged in DMT research. Eventually he left Buddhist practice, and began a deep study of the Hebrew Bible. Initially, he thought that the DMT "spirit molecule" might be responsible for spiritual experiences.

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DMT and the Soul of Prophecy: A New Science of Spiritual Revelation in the Hebrew Bible

Naturally occurring DMT may produce prophecy-like states of consciousness and thus represent a bridge between biology and religious experience.

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DMT: The Spirit Molecule: A Doctor's Revolutionary Research into the Biology of Near-Death and Mystical Experiences

From 1990 to 1995 Dr. Rick Strassman conducted U.S. Government-approved and funded clinical research at the University of New Mexico in which he injected sixty volunteers with DMT, one of the most powerful psychedelics known.

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Science and Spirituality